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Applying
Principles
of Multi-Factor Genetic
Analysis
of Infectious Disease Agents in the Work of the Rospotrebnadzor SAET during Mass Events
I. V. Kuznetsova ; D. V. Efremenko ; A. N. Kulichenko
Problemy osobo opasnyh infekcij, 2018-07 (2), p.68-72
[Peer Reviewed Journal]
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Title:
Applying
Principles
of Multi-Factor Genetic
Analysis
of Infectious Disease Agents in the Work of the Rospotrebnadzor SAET during Mass Events
Author:
I. V. Kuznetsova
;
D. V. Efremenko
;
A. N. Kulichenko
Subjects:
mass events
;
methods of genetic
analysis
;
pathogenic biological agents
;
saet
Is Part Of:
Problemy osobo opasnyh infekcij, 2018-07 (2), p.68-72
Description:
Objective of the study – to develop and test in operation of the Rospotrebnadzor Spesialized Anti-Epidemic Teams (SAET), deployed during the major mass events, the procedure for application of molecular-genetic methods for detection and identification of pathogenic biological agents. Materials and methods. Utilized are the reporting documentation drawn up by the results of work of the specialized anti-epidemic teams of the Rospotrebnadzor on the provision of sanitary epidemiological welfare during Olympic Games 2014 and other important mass events in Sochi in 2015–2017. Results and conclusions. Developed and tested in practice of the Rospotrebnadzor SAET during the major mass events has been procedure for application of molecular-genetic methods, based on structured approach (algorithm) of indication and genetic characterization of PBA. Equipping of the SAET with diagnostic preparations is carried out in accordance with the provision of preparedness for performing investigations by three-level algorithm of molecular-genetic characteristics of pathogens: level I – detection (indication) of a pathogen using PCR, level II – identification of the pathogen genome fragments using PCR, level III – genotyping. Developed procedure was used successfully by the SAET during the Olympic Games 2014 and other important mass events in Sochi in 2015–2017, which allows for recommending it for future use.
Publisher:
Federal Government Health Institution, Russian Research Anti-Plague Institute “Microbe”
Language:
Russian
Identifier:
ISSN: 0370-1069
EISSN: 2658-719X
DOI: 10.21055/0370-1069-2018-2-68-72
Source:
DOAJ Directory of Open Access Journals
Links
View record in Directory of Open Access Journals$$FView record in $$GDirectory of Open Access Journals
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