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Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation

Griffiths, Paul D, Prof

The Lancet infectious diseases, 2012-10, Vol.12 (10), p.790-798 [同儕審閱期刊]

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題名:
Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation
著者: Griffiths, Paul D, Prof
主題: Age Factors ; AIDS-Related Opportunistic Infections ; Biological and medical sciences ; Critical Care ; Cytomegalovirus - immunology ; Cytomegalovirus Infections - immunology ; Cytomegalovirus Infections - prevention & control ; Cytomegalovirus Infections - transmission ; Cytomegalovirus Vaccines ; General aspects ; Human infectious diseases. Experimental studies and models ; Human viral diseases ; Humans ; Infectious Disease ; Infectious Disease Transmission, Vertical - prevention & control ; Infectious diseases ; Mass Vaccination ; Medical sciences ; Organ Transplantation ; Primary Prevention ; Secondary Prevention ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids
所屬期刊: The Lancet infectious diseases, 2012-10, Vol.12 (10), p.790-798
描述: Summary Cytomegalovirus is the most frequent cause of intrauterine infection and the commonest infectious agent to affect allograft recipients, yet the virus is acknowledged rarely as an occupational hazard for women of childbearing age or as a nosocomial infection. The potential role of cytomegalovirus in hastening the death of patients with AIDS, elderly people, individuals admitted to intensive-care units, and the general population is not emphasised. Development of vaccines against this important human pathogen has been delayed by reluctance to initiate proof-of-concept studies, but after recent trials, protection is a distinct possibility. Cytomegalovirus deserves to be eliminated from selected populations by means of universal immunisation as soon as suitable vaccines become licensed. This action should control disease in neonates and transplant recipients and could provide substantial additional benefits if other disease associations prove to be causal.
出版者: London: Elsevier Ltd
語言: 英文
識別號: ISSN: 1473-3099
EISSN: 1474-4457
DOI: 10.1016/S1473-3099(12)70197-4
PMID: 23017365
CODEN: LANCAO
資源來源: Elsevier ScienceDirect Journals Complete

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Burden of disease associated with human cytomegalovirus and prospects for elimination by universal immunisation

Griffiths, Paul D, Prof

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