skip to main content
訪客
個人書架
我的帳戶
登出
登入
This feature requires javascript
檢索首頁
圖書館首頁
電子期刊
引用參考文獻查詢
指定參考書查詢
新書通報
標籤查詢
線上輔助
語言:
English
繁體中文
This feature required javascript
Search in:
選擇瀏覽清單
Search For:
Clear Search Box
Search in:
按題名
按主題
按作者
Browse vid input
簡單檢索
This feature requires javascript
The pathogenesis of human cytomegalovirus
Griffiths
,
Paul
; Baraniak, Ilona ; Reeves, Matt
The Journal of pathology, 2015-01, Vol.235 (2), p.288-297
[同儕審閱期刊]
可取得全文
引用
被引用
線上檢視
詳細格式
評論和標籤
相關文章推薦
FullText@NUTN
引用次數
This feature requires javascript
傳送到
加入個人書架
從個人書架中移除
E-mail
列印
永久連結
引用
EndNote
導出 RiS
This feature requires javascript
題名:
The pathogenesis of human cytomegalovirus
著者:
Griffiths
,
Paul
;
Baraniak, Ilona
;
Reeves, Matt
主題:
Animals
;
Antiviral Agents - therapeutic use
;
congenital
;
Cytomegalovirus - drug effects
;
Cytomegalovirus - genetics
;
Cytomegalovirus - immunology
;
Cytomegalovirus - pathogenicity
;
Cytomegalovirus Infections - drug therapy
;
Cytomegalovirus Infections - epidemiology
;
Cytomegalovirus Infections - immunology
;
Cytomegalovirus Infections - pathology
;
Cytomegalovirus Infections - transmission
;
Cytomegalovirus Infections - virology
;
Cytomegalovirus Vaccines - therapeutic use
;
Genotype
;
Host-Pathogen Interactions
;
Human cytomegalovirus
;
Humans
;
pre-emptive therapy
;
Prognosis
;
Risk Factors
;
threshold
;
transplantation
;
viraemia
;
Virulence
所屬期刊:
The Journal of pathology, 2015-01, Vol.235 (2), p.288-297
描述:
Human cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft recipient and AIDS patients. More recently, it has been recognized as a pathogen for those admitted to intensive care units, for the elderly and for the general population. The epidemiology and molecular and cellular pathology of this virus are summarized to provide an overarching model of pathogenesis, able to account for these varying clinical presentations. In brief, HCMV has the potential to spread in the bloodstream to all organs, but only produces overt disease if the viral load increases to high levels. This is normally prevented by a robust immune response, so that the infected individual usually remains asymptomatic. However, this benefit comes at the cost of committing more and more immunological resources to controlling HCMV with time, so that the overall function of the immune system is impaired. Fortunately, recent progress in developing novel antiviral drugs and vaccines suggests the possibility that the diverse effects of HCMV may soon become controllable at the individual and population level, respectively. Copyright © 2014 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
出版者:
Chichester, UK: John Wiley & Sons, Ltd
語言:
英文
識別號:
ISSN: 0022-3417
EISSN: 1096-9896
DOI: 10.1002/path.4437
PMID: 25205255
資源來源:
Wiley Online Library All Journals
Wiley Online Library Full Collection 2020
連結
View this record in MEDLINE/PubMed
This feature requires javascript
This feature requires javascript
返回到檢索清單
This feature requires javascript
This feature requires javascript
正在檢索遠程資料庫,請稍等
查詢:
在
scope:("NUTN"),scope:(NUTN_ALEPH),scope:(NUTN_IR),scope:(NUTN_SFX),primo_central_multiple_fe
顯示現有記錄
This feature requires javascript
This feature requires javascript